| 目次 |
| 专刊 合成生物学：回顾与展望 |
| 编者按 ------------------------------------------------------------------------------------------------------------------------1131 |
| 序言 张先恩 ------------------------------------------------------------------------------------------------------------------------1132 |
| 总论 |
| 合成生物学：开启生命科学“会聚”研究新时代 赵国屏 ------------------------------------------------------------------------------------------------------------------------1135 |
| 关键技术 |
| 符合工程化需求的生物元件设计 崔颖璐 吴 边 ------------------------------------------------------------------------------------------------------------------------1150 |
| 人工基因线路的研究进展和未来挑战 娄春波 杜 沛 孟凡康 季翔宇 张益豪 ------------------------------------------------------------------------------------------------------------------------1158 |
| 面向生物合成的代谢工程策略设计 马红武 陈修来 袁倩倩 刘立明 孙际宾 ------------------------------------------------------------------------------------------------------------------------1166 |
| DNA的合成、组装及转移技术 卢俊南 罗周卿 姜双英 沈 玥 吴 毅 杨焕明 元英进 戴俊彪 ------------------------------------------------------------------------------------------------------------------------1174 |
| 基因编辑技术：进展与挑战 卢俊南 褚 鑫 潘燕平 陈映羲 温 栾 戴俊彪 ------------------------------------------------------------------------------------------------------------------------1184 |
| 人工细胞的表型测试与分选：构建从光谱学到遗传学的桥梁 马 波 徐 健 ------------------------------------------------------------------------------------------------------------------------1193 |
| 基因组的设计与工程化构建 薛小莉 覃重军 ------------------------------------------------------------------------------------------------------------------------1205 |
| 应用领域 |
| 合成生物学工业应用的现状和展望 曾 艳 赵心刚 周 桔 ------------------------------------------------------------------------------------------------------------------------1211 |
| 合成生物学的医学应用研究进展 崔金明 王力为 常志广 臧中盛 刘陈立 ------------------------------------------------------------------------------------------------------------------------1218 |
| 植物天然产物合成生物学研究 戴住波 王 勇 周志华 李盛英 张学礼 ------------------------------------------------------------------------------------------------------------------------1228 |
| 光合作用合成生物学研究现状及未来发展策略 朱新广 熊 燕 阮梅花 刘 晓 徐 健 钟 超 ------------------------------------------------------------------------------------------------------------------------1239 |
| 平台建设 |
| 合成生物学研究的工程化平台 崔金明 张炳照 马迎飞 傅雄飞 王 猛 刘陈立 ------------------------------------------------------------------------------------------------------------------------1249 |
| 中国科学院合成生物学重点实验室 中国科学院分子植物科学卓越创新中心/植物生理生态研究所 ------------------------------------------------------------------------------------------------------------------------1258 |
| 政策与社会问题 |
| 创新政策体系 保障合成生物学科技与产业发展 刘 晓 曾 艳 王力为 周光明 熊 燕 ------------------------------------------------------------------------------------------------------------------------1260 |
| 设计生命：合成生物学的安全风险与伦理挑战 李真真 董永亮 高旖蔚 ------------------------------------------------------------------------------------------------------------------------1269 |
| 合成生物学：回顾与展望 ------------------------------------------------------------------------------------------------------------------------封面 |
| 中国科学院天津工业生物技术研究所 ------------------------------------------------------------------------------------------------------------------------封二 |
| 中国科学院分子植物科学卓越创新中心/植物生理生态研究所中国科学院合成生物学重点实验室 ------------------------------------------------------------------------------------------------------------------------插页一 |
| 中国科学院深圳先进技术研究院合成生物学研究所 ------------------------------------------------------------------------------------------------------------------------插页二 |
| 中国科学院青岛生物能源与过程研究所单细胞拉曼分选仪 ------------------------------------------------------------------------------------------------------------------------封三 |
| 欢迎订阅《中国科学院院刊》 ------------------------------------------------------------------------------------------------------------------------封四 |
| CONTENTS |
| Synthetic Biology: Retrospect and Prospect |
| Editorial ------------------------------------------------------------------------------------------------------------------------1131 |
| Preface ZHANG Xianen ------------------------------------------------------------------------------------------------------------------------1132 |
| General Theory |
| Synthetic Biology: Unsealing the Convergence Era of Life Science Research ZHAO Guoping ------------------------------------------------------------------------------------------------------------------------1135 |
| Key Technology |
| Biological Components Design for Engineering Requirements CUI Yinglu et al. ------------------------------------------------------------------------------------------------------------------------1150 |
| Development and Challenges of Synthetic Genetic Circuits LOU Chunbo et al. ------------------------------------------------------------------------------------------------------------------------1158 |
| Design of Metabolic Engineering Strategies for Biosynthesis of Valuable Products MA Hongwu et al. ------------------------------------------------------------------------------------------------------------------------1166 |
| Technologies for DNA Synthesis, Assembly, and Transplantation LU Junnan et al. ------------------------------------------------------------------------------------------------------------------------1174 |
| Advances and Challenges in Gene Editing Technologies LU Junnan et al. ------------------------------------------------------------------------------------------------------------------------1184 |
| Phenotyping and Sorting of Synthetic Cells: Building Bridge from Spectroscopy to Genetics MA Bo et al. ------------------------------------------------------------------------------------------------------------------------1193 |
| Genome Design and Engineering Construction XUE Xiaoli et al. ------------------------------------------------------------------------------------------------------------------------1205 |
| Application |
| Current Situations and Perspectives of Industrial Applications of Synthetic Biology ZENG Yan et al. ------------------------------------------------------------------------------------------------------------------------1211 |
| Progress of Synthetic Biology Research in Medical Applications CUI Jinming et al. ------------------------------------------------------------------------------------------------------------------------1218 |
| Synthetic Biology for Production of Plant-derived Natural Products DAI Zhubo et al. ------------------------------------------------------------------------------------------------------------------------1228 |
| Research Status and Future Development Strategies of Synthetic Biology in Photosynthesis ZHU Xinguang et al. ------------------------------------------------------------------------------------------------------------------------1239 |
| Platform Construction |
| Engineering Platforms for Synthetic Biology Research CUI Jinming et al. ------------------------------------------------------------------------------------------------------------------------1249 |
| CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, CAS ------------------------------------------------------------------------------------------------------------------------1258 |
| Policy and Social Issue |
| Innovative Policy System to Ensure the Development of Synthetic Biology LIU Xiao et al. ------------------------------------------------------------------------------------------------------------------------1260 |
| Design Life: Safety Risks and Ethical Challenges in Synthetic Biology LI Zhenzhen et al. ------------------------------------------------------------------------------------------------------------------------1269 |