Abstract:The Oceans account for 71% of the Earth’s surface and are rich in the most advantageous and characteristic resources of marine microbes.The research on diversity is the key point for exploring and exploiting marine microbial resources.Giving attention to species diversity and genetic diversity of marine microbes,discovering novel metabolites with multiple functions,revealing key secondary metabolic process and the main regulation mechanisms in marine microbes,and developing a new technology of biosynthesis,are the important foundation for discovering innovative drugs and developing functional products with characteristics.The present paper has reviewed the recent advances in the four research areas of marine microbial species diversity,genetic diversity,chemical diversity and metabolic diversity in China.