Abstract:Geo-information science is one of the branches of geography.Its methodology research,on one hand,is influenced by both scientific philosophy and methodology of geography,and on the other hand,is the result of summarization and induction from the cases which were extracted from plenty of scientific research achievements,projects,software and hardware products and large quantity of examples of the subject.The research is launched under the background of the need of the times for this discipline and national forward-looking layout.In this paper,the philosophical conception and practical conception of geo-information science methodology are expounded at first,including six points of relationship which should be treated well during the research.Secondly,the methodology structure system is set up,composed of three parts,i.e.,geographic information ontology,six scientific methods and seven technological methods.Thirdly,the specific feature of geographic information and its relationship with methodology are analyzed and expounded.Finally,the innovation mechanism and strategy of geo-information science methodology are discussed.