Abstract:With high resolutions at spatial/energy scales and characteristic of localized nano-probe, scanning tunneling microscopy (STM) has become an important tool to perform spatial and structural manipulations, modulate and control physical/chemical properties for single molecule systems in recent years. It can manipulate single molecules and their components to move in various modes and even induce chemical reactions. By external fields such as electronic effect, STM may also modulate quantum states of single molecule systems, thus it has huge potentials for application in many fields including explorations of new types of materials, designs of nano-devices, studies and controls of chemical reactions, etc.