Abstract:Under the support of first nature (natural endowments) and second nature (traffic and location), Chinese regional development has formed a center-hinterland structure based on the central place theory. After the emergence of third nature marked by informationization and human capital conditions, regional development needs the instruction of new ideas and new modes. A hub-network structure allows the third nature, complies with the political logic of regional fairness, and reflects the economic ideas of free development. Under the influence of flat network organization theory, it also puts a high value on the regional leadership, which will form a new regional pattern with division of labor based on specialization for the overall coordination and integration of collaboration.