Abstract:The Chinese Academy of Sciences(CAS) is the initiator, advocator, and practitioner in poverty reduction using science and technology.In 30 years of poverty reduction, CAS proposed a series of models in poverty alleviation creatively, such as "relocation house places model", "allopatry shareholding model", "technology introduction model", and "rely on field observation stations model".These have developed new ways and made great contribution to promote the regional economy in poverty counties.In this paper, based on comprehensive review of poverty reduction history carried out by CAS, we describe the main points of the implementation in accurate poverty alleviation.