Abstract:To cope with the critical situation of biological security has currently become a significant aspect in national security. Facing the borderless, complexity, devastation, and unpredictability of biological threat factors, and taking its advantages in multi-disciplinary integration, the Chinese Academy of Sciences (CAS) sets up the BioSafety Network platform based on one BioSafety Level 4 (BSL-4) laboratory and several BSL-3 laboratories, constructs the biological security research system, enhances the defending ability including surveillance, detection, disinfection, prevention, and treatment against highly infectious virus, invasive species, and other biological threat factors, improves management system, emphasizes international cooperation and talent recruit, and initiates new research projects. Thus, the CAS will play an important role in China's biological security.