Abstract:Six perspectives, from which materials and their manufacturing and fabrication system are demostrated, are as follows. (1) How could materials science meet the challenge of ever-increased development of advanced technologies? (2) The stories of basic knowledge of microstructure evolution. (3) Newly-developed and developing industry chains are output of multidisciplinary integration occurred in advanced technologies. (4) What could we learn from global experience of novel materials and their manufacturing and fabrication? (5) Designing Chinese knowledge system of novel materials and their manufacturing and fabrication. And (6) where is our roadmap? What are urgent tasks and implementation measures for the 13th Five-Year Plan? In order to catch up and be comparable with global competition in fields of industries, we propose that the creation of novel materials and their manufacturing and fabrication system is one of the forward-looking strategies. In order to build a strong state with advanced and powerful manufacturing and fabrication system, it is then one of the key factors to fulfill the so called five development concepts of “innovation, harmony, green, open, and sharing”.