Abstract:The culture of science in nature, is a system of values, behavioral rules, and social regulations, and also an attitude to living, a way to working followed by the people consciously or unconsciously. It plays an important role in promoting progress of modernization of nations and peoples, whose impacts out distanced scientific communities. In its formulation and evolution, the culture of science has been fusing with the culture of humanity and art, becoming a megaculture with mass public engagement, rather than the scientists' minority culture. Based on universal principles, the culture of science shows characteristics of different peoples, reflecting great tensions that support to build a global power of science and technology. From this view, scientists have the responsibility to nurture and develop culture of science, meanwhile, researches on culture of science should properly combine academic studies with requirement of policies. Consequently, it is the responsibility of building culture of science that needs to be undertaken by scientific and academic communities, and also the public in society.