Abstract:For decades, antimicrobials have played a key role in helping and protecting the sound development of animal husbandry. Undoubtedly, for intensive farming, antibiotics will still be one of the essential strategies for preventing and treating the bacterial infectious disease in a very long time. Nevertheless, due to the widely use of antimicrobials, the resistant bacteria and antimicrobial resistance have emerged, which become a severe challenge threatening the whole public for returning to the "pre-antibiotic era". For comprehensively understanding of this issue, here this study focuses on the pros and cons of using antibiotics in livestock, global experience in balancing the use of drugs and the control of antimicrobial resistance, and the advices and strategies are raised specifically for China.