Abstract:The concept of bionics combines biology and engineering technology to provide people with new principles, methods, and ways to improve and create new equipment, promote technological innovation, and solve technical problems in the most flexible, efficient, reliable, and economical way. Although information technology continues to develop, it still faces many challenges in the era of big data and intelligence. With the explosive growth of massive data, the demand of storage, calculation, and analysis, and its energy consumption and efficiency challenges, information technology is urgently needed to find a new development direction. Inspired by biotechnology, it is becoming an international frontier research direction to find information technology innovation scheme from biological structure. As active new research fields, DNA data storage and neural morphological computation as well as related research are representative directions, which have broad future development prospects. Based on the development status and trend of these two research directions, this study attempts to analyze the motivation, trend, and prospect of information technology development inspired by biotechnology. The next two decades will be an important time window for the cross integration of life field and information field. By learning and simulating from life system, and drawing on the new ideas, principles and theories provided by biotechnology research, the information field will produce a number of subversive technologies and applications, and it will affect the entire academic and industrial sessions.