Abstract:In recent years, with the growing population, the significant changes in climate, the constant emergence of extreme weather and natural disasters, as well as the influence of the disruptive development of modern biotechnology and the globalization of economic and trade processes, the global biosafety risks and destabilizing factors have been increased, and the new outbreaks of infectious diseases is also increased explosively. These brought new challenges for the modernization of China's biosafety governance system and governance capabilities. Aiming at the main risks and challenges of global biosafety, this work analyzes the contents and main points of national biosafety strategy and strategic studies in the US, UK, Japan, and other countries since 2018. Meanwhile, some suggestions are put forward to strengthen the construction of national biosafety strategy system, laws and regulations systems, and collaborative innovation system, and further improve the national biosafety governance system and governance capacity building.