Abstract:How to balance the relationship between the development of data and personal information protection, is an important problem affecting the development of digital economy of the country, especially in the field of sensitive personal data such as medical data. In the medical field, Japan formed its own regulation system according to its domestic situation. Based on the experiences of Japan, this study proposed some suggestions which would improve our concerned systems. (1) China is not yet having specific personal information protection legislation, let alone a set of effective personal information protection legal system. So, a special law should be formulated to protect the right of personal information, and be perfected as soon as possible from the aspect of protection of right of privacy of the citizen in China. (2) China shall attach great importance to the development and application of personal data and medical data, and design the relevant regulations. (3) Anonymity and opt-out requirements are used in personal information protection. Japan has accumulated much mature experience in medical data regulation, which is worthy of being drawn upon by regulators in China.