Abstract:Persistent organic pollutants (POPs) have complex structures with many congeners and isomers. Although they are trace levels in environmental media and organisms, they are toxic to both humans and wildlife. The determination of trace POPs is a great challenge for environmental analysis. The POPs monitoring in China started 40 years ago. After the unremitting efforts of three generations of the Chinese scientists, and with the financial support of national scientific and technological projects, the POPs monitoring capacity is greatly improved, laying a solid scientific foundation for POPs being included into national routine monitoring. This article describes the leap-forward development of POPs monitoring technology in China, and introduces the contributions of Chinese scientists to the implementation of the “Stockholm Convention on Persistent Organic Pollutants” in carrying out domestic POPs monitoring and POPs monitoring in the Asia-Pacific region. The demand and research prospects for future POPs monitoring are put forward.