Abstract:The ocean is essential to country's strategic interests and common destiny of mankind, and therefore equipment of various kinds is urgently needed for all-around and multi-dimensional ocean observation and exploration. This article brief introduced the two technological approaches of nuclear energy supply for underwater observation and exploration equipment and relevant exchange technologies of nuclear heat to electric power, quantitatively summarized the applicability of nuclear energy supply on all kinds of equipment, discussed the nuclear safety issues thereon, and then recommended that the technology research of radioisotope fabrication and separation and the construction of relevant facility, the development of individual reactor and the construction of relevant common facility, the technology research of thermoelectric conversion, and the research of relevant nuclear safety issues, should be special supported.