Abstract:China has officially established the first batch of national parks in 2021 and such construction is entering a high-speed stage. National parks of the country basically originate from existed protected areas, and face series of long-standing problems and challenges, such as over simplified administration, low community participation, and prominent contradictions between ecological conservation and social development. The Man and the Biosphere (MAB) Programme is the first flagship project of United Nations Educational, Scientific and Cultural Organization (UNESCO) for biodiversity and cultural diversity conservation, biosphere reserve is its implementation platform, which has accumulated a lot of useful experience in biodiversity conservation, sustainable development, management and governance models, and regular evaluation. This study summarizes the theories and practice of biosphere reserves related to the construction of national parks. Several suggestions are concluded for the establishment and management of national park, including strengthening the excavation, integration and utilization of cultural diversity, promoting the participation of communities, innovating governance models, establishing a mechanism for realizing the value of ecological products and brand appreciation, and formulating a comprehensive evaluation system.