Abstract:Urban science is the study of urban problems from the viewpoint and by method of system science. At present, China’s urbanization rate has reached 65.22%. Urban development has entered a new period of quality improvement and structural adjustment, and the progress of information technology and the development of information industry have also brought new opportunities for urban science. After reviewing the theoretical basis of urban science put forward by Qian Xuesen, drawing on the cutting-edge trends of international urban science research, combined with the goal support, key challenges and application scenarios of China’s new smart city construction, the study puts forward the requirements of times to improve the level of urban science research, so as to give new ideas and connotations to the future development of urban science.