Abstract:Located in the Wumeng Mountain region of southern China, encompassed with vast range of stretching between Sichuan, Guizhou, and Yunnan Provinces, Shuicheng, Guizhou Province, has long been plagued by karst landscapes, rocky desertification along with the poverty that comes with it. It used to be a national key county for poverty alleviation and development, and by the end of 2016, its poverty incidence rate still was 18.9%. As the designated support organization of Shuicheng, the Chinese Academy of Sciences (CAS), during the battle against poverty, making use of the local ecological environment and resource, and its industrial foundation, promoted a large number of scientific and technological achievements transformation, and helped Shuicheng build characteristic industries in accordance with local conditions, which helped remove Shuicheng from the poverty county list in March 2020 successfully. In 2020, Shuicheng stepped on the road towards rural vitalization. CAS will continue to help Shuicheng upgrade its industries in a scientific way, improve its quality and efficiency, so that the county can go well on the road to vitalization.