Abstract:Intellectual property security is the main battlefield of national security, and strengthening intellectual property security review is an important measure to protect national security and improve intellectual property security protection in the field of intellectual property. In the new era, the security review mechanism of intellectual property rights transfer and its implementation are facing double pressures worldwide, which need to be further adjusted and improved. This study analyzes the institutional games and challenges brought about by the changes in the international situation of intellectual property rights transfer, clarifies the requirements of the current overall national security concept and the strategy of self-reliance and self-reliance in science and technology for intellectual property rights transfer, sorts out many problems existing in the security review mechanism and specific implementation of intellectual property rights transfer, and puts forward the optimization ideas for improving the security review system and implementing the system. In theory, the institutional dilemma of the security review mechanism of intellectual property rights transfer abroad is clarified, which can provide research reference for the security review of intellectual property rights transfer in China in practice.