Abstract:Since the 18th National Congress of the Communist Party of China, China’s regional coordinated development has shown a sound trend through measures such as poverty alleviation, ecological civilization construction, and the implementation of major regional strategies. During the 15th Five-Year Plan period, China’s regional coordinated development is faced with the huge challenge of global resource and environmental supply shortage, slow and weak consumption growth in China and the world’s major economies, multi-sided suppression by developed countries, and continuous catch-up by developing countries with low-cost advantages. This study first puts forward some new academic thoughts, such as the equilibrium theory of spatial development, the spatial organization theory of node source and sink in economic network, and the spatial convergence theory of innovation chain-industry chain. On the basis of theoretical innovation, it has clarified the strategic key points of attaching equal importance to creating new driving forces for the development of developed areas and fostering the development of growth poles in underdeveloped areas, as well as taking coordinated regional development as the approach to Chinese-style modernization in the near future. The research holds that scientific and technological innovation plays a leading role in promoting regional coordinated development. Building a regional model of “scientific and technological innovation system + new quality productivity layout” according to local conditions, forming a new development pattern of comprehensive functional areas, promoting the westward shift of the focus of resource utilization industry layout, and attaching importance to cultivating the function of growth poles in key areas should become the main paths for regional coordinated development. Finally, the strategic and fundamental role of the major functional zoning is discussed.