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投稿时间：2024-08-04
投稿时间：2024-08-04
中文摘要: 近年来，细胞作为一种新型药物，在疾病治疗中取得了巨大进展，尤其在多种难治性疾病治疗中获得了前所未有的成功，迅速成为全球的研究热点。文章介绍了细胞治疗的概念及其发展现状；根据细胞治疗药物的分类，系统总结了不同类型细胞作为药物在相应疾病治疗中的研究亮点；最后，对我国细胞治疗领域的整体发展趋势进行展望，特别关注了在基础研究、细胞药物化、工艺研发，以及政策层面如何进一步推动细胞药物的临床转化应用和产业化。
Abstract:Cell-based medicinal products are a breakthrough that has been proven to treat previously incurable diseases, making them a topic of global interest. This review delves into the current state and progress of cell therapy, highlighting the remarkable therapeutic effects of various types of cell-based medicinal products. We specifically explore the potential development of cell-based medicinal products in China, focusing on promoting clinical translation and commercialization. We propose necessary actions to achieve these goals, such as fostering cutting-edge basic research, innovative therapeutic approaches, scalable manufacturing processes, and policy changes.
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基金项目:中国科学院战略性先导科技专项（A类）（XDA16020201），国家自然科学基金（32221002）和上海市科学技术委员会“科技创新行动计划”（22JC1403001）
引用文本：
惠利健*,袁湘,吴婧琪.细胞治疗药物：进展与展望[J].中国科学院院刊,2024,39(8):1434-1446.
HUI Lijian*,YUAN Xiang,WU Jingqi.Cell-based medicinal products: Progress and perspectives[J].Bulletin of Chinese Academy of Sciences,2024,39(8):1434-1446.
惠利健*,袁湘,吴婧琪.细胞治疗药物：进展与展望[J].中国科学院院刊,2024,39(8):1434-1446.
HUI Lijian*,YUAN Xiang,WU Jingqi.Cell-based medicinal products: Progress and perspectives[J].Bulletin of Chinese Academy of Sciences,2024,39(8):1434-1446.
