林其谁.分子与细胞生物学的一些进展[J].中国科学院院刊,2006,(6):479-485.

林其谁
中国科学院上海生命科学研究院生物化学与细胞生物学研究所
Lin Qishui
Institute of Biochemistry and Cell Biology,Shanghai Institutes for Biological Sciences,CAS,200031 Shanghai

         RNA;表观遗传调控;合成生物学;胚胎干细胞;活细胞结构;活细胞分子相互作用;纳米生物学

        RNA;epigenomics;synthetic biology;embryonic stem cell;structure of living cells;molecular;interaction in vivo;nano-biology

        分子以及分子间的相互作用是生命活动的基础,细胞是最小的生命单位。近年来在基因组、非编码蛋白质的RNA与表观遗传调控、合成生物学、活体细胞的结构与细胞内分子相互作用、胚胎干细胞的研究、纳米技术与分子细胞生物学的交叉结合等方面进展很快。本文就这些方面做一介绍并就国内今后的发展提出了建议。

        Molecules and interactions between molecules are fundamental to life activities.Cell is the smallest unit of life.In recent years,progresses were very significant in a number of fields,e.g.genomics,non protein-coding RNA and epigenomics;synthetic biology,in vivo cell structure and molecular interaction,embryonic stem cell, nano-technology in cell biology.The present paper gives a brief overview on those fields and certain suggestions are provided for further development in China.