Abstract:In the context of the new round of scientific and technological revolution and industrial transformation, the related issues of techno-economic security have become the focus of major countries and regions. From the perspective of discipline construction, basic theory has been studied on key questions such as why, what, and how to evaluate. This study analyzes the importance and urgency, puts forward key issues of techno-economic security that should be paid attention to at different levels, such as technology, enterprise, industry, and country or region. A mechanism framework of the occurrence and evolution of techno-economic security is constructed, which is composed of four nodes: environmental induction, factor transmission, multiple feedback, and spatio-temporal evolution. On this basis, the TMAPS (technology-marketactors-policy-security) model and index framework of techno-economic security evaluation are formed. The study is helpful to further clarify the connotation and boundary of techno-economic security, and provide theoretical and methodological support for strengthening the evaluation of techno-economic security and guaranteeing the level of techno-economic security.