Abstract:The International Scientific and Technological Organization（ISTO）gathers and integrates a large number of global innovation resources. ISTO is the advocate of scientific and technological (S&T) policies and regulations, the formulator of international technical standards and rules, as well as the coordinator of advanced concepts and ideas. With the general trend of globalization in today’s world, the developmental level of ISTO has become the important manifestations of a country’s S&T civilization and comprehensive competence. Nevertheless, there still appear many problems and challenges in current situations of ISTOs in China, such as the low number of the ISTOs, the lack of a mature set of introduction, management, and services mechanism. From the perspective of international organizations, this study firstly summarizes the important function of ISTOs, afterwards, it combs the related supportive policies abroad and domestic that are from all localities and government departments in present years. In combination of the current status of ISTOs in China, the problems and obstacles in initiating and establishing the ISTOs, attracting ISTOs to settle in China, as well as participating in the affairs of ISTOs are studied thoroughly, and relevant countermeasures and suggestions are also raised.